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KMID : 0545120140240030354
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Journal of Microbiology and Biotechnology
2014 Volume.24 No. 3 p.354 ~ p.358
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Lycorine: A Potential Broad-Spectrum Agent Against Crop Pathogenic Fungi
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Jin-Wen Shen
Yuan Ruan
Wei Ren
Bing-Ji Ma
Xiao-Long Wang
Chun-Feng Zheng
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Abstract
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A screening test showed that lycorine exhibited significant antifungal activity against 24 pathogenic crop fungi at concentrations of 500 μg/ml and 100 μg/ml, respectively. Fusarium graminearum was selected for antifungal mechanism studies by observing its mycelial morphology and investigating the variations in its conductivity. In addition, the substance absorption and metabolism of F. graminearum were explored. The mechanism was revealed as being one by which lycorine destroyed the cellular membrane and further influenced substance absorption and cell metabolism.
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KEYWORD
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Lycorine, anti-fungus activities, anti-fungal mechanism, Fusarium graminearum
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